Purchase
Description
Alirocumab biosimilar is a human monoclonal antibody (IgG1 isotype) that targets proprotein convertase subtilisin kexin type 9 (PCSK9), is a PCSK9 inhibitor produced by recombinant DNA technology in Chinese Hamster Ovary cell suspension culture. Alirocumab biosimilar consists of two disulfide-linked human heavy chains, each covalently linked through a disulfide bond to a human kappa light chain. A single Nlinked glycosylation site is located in each heavy chain within the CH2 domain of the Fc constant region of the molecule. The variable domains of the heavy and light chains combine to form the PCSK9 binding site within the antibody. Alirocumab biosimilar has an approximate molecular weight of 146 kDa.
Alirocumab biosimilar is supplied at a concentration of 150 mg/mL as a sterile, preservative-free, clear, colorless to pale yellow solution, which contains 6 mM histidine, 0.1 mg/mL polysorbate 20, 100 mg/mL sucrose, and Water for Injection, to pH 6.0.
Statement: this product is used for R&D
only, not for clinical usage.
Properties
|
Name
|
Alirocumab biosimilar
|
|
CAS
NO.
|
1245916-14-6
|
|
Type
|
Whole
antibody
|
|
Source
|
Human
|
|
Target
|
PCSK9
|
|
Clone
|
Monoclone
|
|
Molecular
Weight
|
146 kDa
|
|
Formula
|
C6472H9996N1736O2032S42
|
|
Antibody
Form
|
Purified immunoglobulin
|
|
Physical
Form
|
Solution
|
|
Grade
Standard
|
Medicine Grade
|
|
Place
of Origin
|
China (Mainland)
|
|
Storage
|
-70±15℃ for long-term
storage, 2-8℃ for short-term storage, away from light.
|
Supply Ability
20 kilogram per year, Minimum order quantity is 1 gram.
Price
Inquiry
Material Safety Data Sheet
If you need more information, please contact us.
Certificate Of Analysis
/en/UploadFile/file/201805/20180508153699979997.rar
Detail information about the product please refer the website below:
https://en.wikipedia.org/wiki/Alirocumab
|
