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Description
Herceptin (trastuzumab) is a humanized IgG1 kappa monoclonal antibody that selectively binds with high affinity to the extracellular domain of the human epidermal growth factor receptor 2 protein, HER2. Trastuzumab is produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary) culture containing the antibiotic gentamicin. Gentamicin is not detectable in the final product.
Trastuzumab is a sterile, clear, colorless liquid of pH approximately 6.0, which may contain a small amount of easily visible, white, amorphous trastuzumab particulates. trastuzumab is supplied at a concentration of 21 mg/mL, which contains 19.09 mg/mL α,α-trehalose dihydrate, 0.475 mg/mL L-histidine HCl monohydrate, 0.305 mg/mL L-histidine, and 0.085 mg/mL polysorbate 20, Water for Injection, and no preservatives.
Properties
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Name
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trastuzumab
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CAS
NO.
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180288-69-1
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Type
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Whole
antibody
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Source
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humanized (from mouse)
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Target
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HER2/neu
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Clone
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Monoclone
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Formula
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C6470H10012N1726O2013S42
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Molecular
Weight
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146 kDa
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Antibody
Form
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Purified immunoglobulin
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Physical
Form
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Solution
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Grade
Standard
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Medicine Grade
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Place
of Origin
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China(Mainland)
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Storage
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-70±15℃ for long-term
storage, 2-8℃ for short-term storage, away from light.
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Supply Ability
20 kilogram per year, Minimum order quantity is 1 gram.
Price
Inquiry
Material Safety Data Sheet
If you need more information, please contact us.
Certificate Of Analysis
/en/UploadFile/file/201805/20180508155257305730.rar
Detail information about the product please refer the website below：
https://en.wikipedia.org/wiki/Trastuzumab
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