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Fusion Protein
Name:Aflibercept biosimilar
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Description

Aflibercept biosimilar is a recombinant fusion protein consisting of portions of human VEGF receptors 1 and 2 extracellular domains fused to the Fc portion of human IgG1 formulated as an iso-osmotic solution for intravitreal administration. Aflibercept biosimilar is a dimeric glycoprotein with a protein molecular weight of 97 kilodaltons (kDa) and contains glycosylation, constituting an additional 15% of the total molecular mass, resulting in a total molecular weight of 115 kDa. Aflibercept biosimilar is produced in recombinant Chinese hamster ovary (CHO) cells. 

Aflibercept biosimilar is supplied at a concentration of 40 mg/mL as a sterile, clear, and colorless to pale yellow solution, which contains 10 mM sodium phosphate, 40 mM sodium chloride, 0.03% polysorbate 20, and 5% sucrose, pH 6.2.
Properties

Name

Aflibercept biosimilar

CAS NO.

862111-32-8

Type

a recombinant fusion protein

Source

Human

Target

VEGF

Clone

Monoclone

Molecular Weight

115 kDa

Formula

C4318H6788N1164O1304S32

Antibody Form

Purified immunoglobulin

Physical Form

Solution

Grade Standard

Medicine Grade

Storage

-70±15 for long-term storage, 2-8 for short-term storage, away from light.

Supply Ability

20 kilogram per year, Minimum order quantity is 1 gram.
Price
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Material Safety Data Sheet
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Certificate Of Analysis

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